Tuesday, September 14, 2010

Department of Biochemistry(UDSC)

A two-year programme leads to the award of an M Sc degree in Biochemistry. Students are offered advanced level theory and practical courses in enzymes, proteins, biochemical and biophysical techniques, molecular biology, cell biology, genetic engineering, immunology, developmental biology, metabolomics, proteomics and bioinformatics. The emphasis is on training students for research. This includes work by second-year students in research laboratories to carry out projects under the supervision of faculty members. Students are also required to present critical reviews on various topics in seminars for evaluation.
The Department enrols students for a Ph D degree in Biochemistry and participates actively in the M Phil Programme (Biotechnology), which is jointly run by the Departments of Biochemistry, Biophysics, Microbiology and Genetics. The Department is provided with modern scientific equipments and offers research opportunities in different areas of basic and applied sciences.
The faculty at the Department of Biochemistry has a number of research projects with both basic and applied aspects in different areas of human diseases with its focus on macromolecular delivery, vaccine development and diagnostics. Specific thrust areas include studies on gene regulation and pathogenesis of Mycobacterium tuberculosis, identification and validation of new drug targets against TB, development of vaccine against TB, production of monoclonal antibodies using hybridoma technology for a variety of applications, phage display based identification of immunodominant epitopes for disease identification such as AIDS, hepatitis and tuberculosis, functional genomics, targeted delivery of drugs, toxins and genetic materials using liposomes and nanoparticles as carriers for the treatment of cancerous and infectious diseases, use of Sendai virus envelopes, F-virosomes for encapsulating a variety of macromolecules for basic and applied work such as targeted delivery of DNA vaccines, Structural and molecular understanding of protein folding and stability, regulation of ligand binding in novel haemoglobin, study of haemoglobin disorders, structure-function relationship in dopamine β-hydroxylase. Molecular mechanism of cellular transformation, gene regulation and its aberrations in cancer, design of novel therapeutic strategies against cancer. Photoperception and signal transduction in algal system, blue-light mediated virulence in bacteria, channelopathies and algal biotechnology.
Department has DBT sponsored Bioinformatics Sub-Centre and a National DNA Sequencing facility.
Faculty:
Professors:
    Dr. Anil K. Tyagi (Gene Regulation, Pathogenesis, Drug Targets and Vaccine Development against TB)
    Dr. Vijay K. Chaudhary  (Protein Engineering and Immunodiagnostics)
    Dr. Prahlad.C. Ghosh  (Liposome Technology, Cell Biology, Drug Delivery)
   Dr. Debi P.Sarkar (Virology, Molecular Cell Biology, Drug Delivery)

Readers: Dr. Suman Kundu (Structural Biology)
                 Dr. Alo Nag (Cell Signalling, Cancer Biology)

Lecturer:   Dr. Suneel Kateriya (Protein Chemistry and Membrane Biology)

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